It depends on what "ads not performing well" means. Is he not happy with the volume or cost/lead? Or do the leads he gets not convert well? 

The 18-24 age bracket has spent less than 3% of the total account in the last 30-days. It has brought in leads for as cheap as $8. We can exclude it, but it will not affect account performance. 

We cannot exclude the "unknown" bracket as most of the users in Google have an unknown age. This will be catastrophic to account performance. 

Shane  business is a little bit slower for him, so I was wondering what else we can do. 25% of his clientele is female, if that's helpful info. Should we exclude the 65+?

I can update some targeting, but it will make very little difference in performance. 

Shane  ok thank u!